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Heat oven to 375. Mix baking mix and water until soft dough forms; beat vigorously 20 strokes. Gently smooth into ball on floured board. Knead 5 times . Roll dough 2 inches larger than inverted pie plate. Ease into plate; flute edges.
Cook and stir hamburger until brown, drain. Stir in salt, oregano, pepper, bread crumbs, tomato sauce, onion and green pepper; spread into pie crust. Beat egg and milk, stir in remaining ingredients. Spread over beef mixture. Bake until crust is golden, about 30 minutes.
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