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Meanwhile, thaw beef if frozen. Heat oil in a 12-inch nonstick skillet over medium heat. Peel and coarsely chip the onion, adding it to the pan as you chop. Add the beef and raise the heat to high. Cook, turning and breaking up the meat, and when it begins to crumbloe and brown, add the mushrooms. Cook until their juice is released and the beef is completely browned, about 5 minutes, stirring frequently. Add the vegetable juice, ketchup, garlic powder, celery salt, and oregano. Stir well to mix, then reduce the heat to medium-low.
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Simmer the mixture while the ziti finishes cooking, stirring from time to time. Immediately drain the ziti, add it to the skillet, and cook for 1 minute more to heat through. Remove from the heat and serve.
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